Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E.
Nat Med. 2011 Oct 30;17(11):1498-503. doi: 10.1038/nm.2492.
PMID:22037646
The adipocyte microenvironment and cancer.
Mukherjee A, Bilecz AJ, Lengyel E.
Cancer Metastasis Rev. 2022 Sep;41(3):575-587. doi: 10.1007/s10555-022-10059-x. Epub 2022 Aug 8.
PMID:35941408
Arachidonic Acid in Follicular Fluid of PCOS Induces Oxidative Stress in a Human Ovarian Granulosa Tumor Cell Line (KGN) and Upregulates GDF15 Expression as a Response.
Ma Y, Zheng L, Wang Y, Gao Y, Xu Y.
Front Endocrinol (Lausanne). 2022 May 11;13:865748. doi: 10.3389/fendo.2022.865748. eCollection 2022.
PMID:35634503
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion.
Zou Y, Henry WS, Ricq EL, Graham ET, Phadnis VV, Maretich P, Paradkar S, Boehnke N, Deik AA, Reinhardt F, Eaton JK, Ferguson B, Wang W, Fairman J, Keys HR, Dančík V, Clish CB, Clemons PA, Hammond PT, Boyer LA, Weinberg RA, Schreiber SL.
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.
Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, Lawrence T.
Cell Metab. 2019 Jun 4;29(6):1376-1389.e4. doi: 10.1016/j.cmet.2019.02.016. Epub 2019 Mar 28.
PMID:30930171
Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.
Weiss JM, Davies LC, Karwan M, Ileva L, Ozaki MK, Cheng RY, Ridnour LA, Annunziata CM, Wink DA, McVicar DW.
Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils.
Perego M, Tyurin VA, Tyurina YY, Yellets J, Nacarelli T, Lin C, Nefedova Y, Kossenkov A, Liu Q, Sreedhar S, Pass H, Roth J, Vogl T, Feldser D, Zhang R, Kagan VE, Gabrilovich DI.
Sci Transl Med. 2020 Dec 2;12(572):eabb5817. doi: 10.1126/scitranslmed.abb5817.
PMID:33268511
Targeting lipid metabolism in the treatment of ovarian cancer.
Chaudhry S, Thomas SN, Simmons GE Jr.
Oncotarget. 2022 May 25;13:768-783. doi: 10.18632/oncotarget.28241. eCollection 2022.
PMID:35634242
Therapeutic Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Female Reproductive Diseases.
Liao Z, Liu C, Wang L, Sui C, Zhang H.
Front Endocrinol (Lausanne). 2021 Jun 23;12:665645. doi: 10.3389/fendo.2021.665645. eCollection 2021.
PMID:34248842
Effects of Androgen Excess-Related Metabolic Disturbances on Granulosa Cell Function and Follicular Development.
Liao B, Qi X, Yun C, Qiao J, Pang Y.
Front Endocrinol (Lausanne). 2022 Feb 14;13:815968. doi: 10.3389/fendo.2022.815968. eCollection 2022.