Mechanical Ventilation-induced Diaphragm Atrophy Strongly Impacts Clinical Outcomes.
Goligher EC, Dres M, Fan E, Rubenfeld GD, Scales DC, Herridge MS, Vorona S, Sklar MC, Rittayamai N, Lanys A, Murray A, Brace D, Urrea C, Reid WD, Tomlinson G, Slutsky AS, Kavanagh BP, Brochard LJ, Ferguson ND.
Am J Respir Crit Care Med. 2018 Jan 15;197(2):204-213. doi: 10.1164/rccm.201703-0536OC.
PINK1/Parkin-mediated mitophagy in mechanical ventilation-induced diaphragmatic dysfunction.
Yong H, Zhou Y, Ye W, Li T, Wu G, Chen J, Liu L, Wei J.
Ther Adv Respir Dis. 2021 Jan-Dec;15:1753466621998246. doi: 10.1177/1753466621998246.
Diaphragm Neurostimulation Assisted Ventilation in Critically Ill Patients.
Etienne H, Morris IS, Hermans G, Heunks L, Goligher EC, Jaber S, Morelot-Panzini C, Assouad J, Gonzalez-Bermejo J, Papazian L, Similowski T, Demoule A, Dres M.
Am J Respir Crit Care Med. 2023 May 15;207(10):1275-1282. doi: 10.1164/rccm.202212-2252CP.
Calpains play an essential role in mechanical ventilation-induced diaphragmatic weakness and mitochondrial dysfunction.
Hyatt HW, Ozdemir M, Yoshihara T, Nguyen BL, Deminice R, Powers SK.
Redox Biol. 2021 Jan;38:101802. doi: 10.1016/j.redox.2020.101802. Epub 2020 Nov 25.
AT1 receptor blocker losartan protects against mechanical ventilation-induced diaphragmatic dysfunction.
Kwon OS, Smuder AJ, Wiggs MP, Hall SE, Sollanek KJ, Morton AB, Talbert EE, Toklu HZ, Tumer N, Powers SK.
J Appl Physiol (1985). 2015 Nov 15;119(10):1033-41. doi: 10.1152/japplphysiol.00237.2015. Epub 2015 Sep 10.
Trolox attenuates mechanical ventilation-induced diaphragmatic dysfunction and proteolysis.
Betters JL, Criswell DS, Shanely RA, Van Gammeren D, Falk D, Deruisseau KC, Deering M, Yimlamai T, Powers SK.
Am J Respir Crit Care Med. 2004 Dec 1;170(11):1179-84. doi: 10.1164/rccm.200407-939OC. Epub 2004 Sep 16.
Maintenance of spontaneous breathing at an intensity of 60%-80% may effectively prevent mechanical ventilation-induced diaphragmatic dysfunction.
Luo Z, Han S, Sun W, Wang Y, Liu S, Yang L, Pang B, Jin J, Chen H, Cao Z, Ma Y.
PLoS One. 2020 Mar 4;15(3):e0229944. doi: 10.1371/journal.pone.0229944. eCollection 2020.
Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction.
Sassoon CS, Zhu E, Caiozzo VJ.
Am J Respir Crit Care Med. 2004 Sep 15;170(6):626-32. doi: 10.1164/rccm.200401-042OC. Epub 2004 Jun 16.
Reduction in Ventilation-Induced Diaphragmatic Mitochondrial Injury through Hypoxia-Inducible Factor 1alpha in a Murine Endotoxemia Model.
Li LF, Yu CC, Wu HP, Chu CM, Huang CY, Liu PC, Liu YY.
Int J Mol Sci. 2022 Jan 19;23(3):1083. doi: 10.3390/ijms23031083.
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction.
Whidden MA, McClung JM, Falk DJ, Hudson MB, Smuder AJ, Nelson WB, Powers SK.
J Appl Physiol (1985). 2009 Feb;106(2):385-94. doi: 10.1152/japplphysiol.91106.2008. Epub 2008 Oct 30.
