Rare cancer-specific mutations in PIK3CA show gain of function.
Gymnopoulos M, Elsliger MA, Vogt PK.
Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5569-74. doi: 10.1073/pnas.0701005104. Epub 2007 Mar 21.
PMID:17376864
Setting hinge position distal to the proximal margin of the distal lateral femur reduces the maximum principal strains of the hinge area and risk of hinge fractures.
Tanaka A, Matsushita T, Nakatsuji T, Katsui Y, Nagai K, Nishida K, Mukai T, Kuroda R.