Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumors.
Ibrahim A, Chopra S.
Arch Pathol Lab Med. 2020 May;144(5):655-660. doi: 10.5858/arpa.2018-0370-RS. Epub 2019 Jun 6.
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M.
Nature. 2024 Jan;625(7994):385-392. doi: 10.1038/s41586-023-06857-0. Epub 2023 Dec 20.
Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Martínez-Reyes I, Cardona LR, Kong H, Vasan K, McElroy GS, Werner M, Kihshen H, Reczek CR, Weinberg SE, Gao P, Steinert EM, Piseaux R, Budinger GRS, Chandel NS.
Nature. 2020 Sep;585(7824):288-292. doi: 10.1038/s41586-020-2475-6. Epub 2020 Jul 8.
Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.
Wang X, Zhang X, Cao K, Zeng M, Fu X, Zheng A, Zhang F, Gao F, Zou X, Li H, Li M, Lv W, Xu J, Long J, Zang W, Chen J, Gao F, Ding J, Liu J, Feng Z.
Nat Commun. 2022 Jul 8;13(1):3947. doi: 10.1038/s41467-022-31548-1.
SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ.
Yuan T, Zhou T, Qian M, Du J, Liu Y, Wang J, Li Y, Fan G, Yan F, Dai X, Li X, Wu Y, Dong X, He Q, Zhu H, Yang B.
Hepatology. 2023 Jul 1;78(1):103-119. doi: 10.1002/hep.32621. Epub 2022 Jul 6.
Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation.
Chen X, Sunkel B, Wang M, Kang S, Wang T, Gnanaprakasam JNR, Liu L, Cassel TA, Scott DA, Muñoz-Cabello AM, Lopez-Barneo J, Yang J, Lane AN, Xin G, Stanton BZ, Fan TW, Wang R.
Sci Immunol. 2022 Apr 29;7(70):eabm8161. doi: 10.1126/sciimmunol.abm8161. Epub 2022 Apr 29.
Succinate dehydrogenase is essential for epigenetic and metabolic homeostasis in hearts.
Li W, Quan L, Peng K, Wang Y, Wang X, Chen Q, Cheng H, Ma Q.
Basic Res Cardiol. 2023 Oct 11;118(1):45. doi: 10.1007/s00395-023-01015-z.
Hereditary succinate dehydrogenase-deficient renal cell carcinoma.
Rogala J, Zhou M.
Semin Diagn Pathol. 2024 Jan;41(1):32-41. doi: 10.1053/j.semdp.2023.11.001. Epub 2023 Nov 8.
Mitochondrial myopathies.
DiMauro S, Bonilla E, Zeviani M, Servidei S, DeVivo DC, Schon EA.
J Inherit Metab Dis. 1987;10 Suppl 1:113-28. doi: 10.1007/BF01812852.
Succinate dehydrogenase (SDH) deficiency, Carney triad and the epigenome.
Settas N, Faucz FR, Stratakis CA.
Mol Cell Endocrinol. 2018 Jul 5;469:107-111. doi: 10.1016/j.mce.2017.07.018. Epub 2017 Jul 21.
