Developments in the Treatment of Leber Hereditary Optic Neuropathy.
Chen BS, Yu-Wai-Man P, Newman NJ.
Curr Neurol Neurosci Rep. 2022 Dec;22(12):881-892. doi: 10.1007/s11910-022-01246-y. Epub 2022 Nov 21.
Emerging therapies for mitochondrial diseases.
Hirano M, Emmanuele V, Quinzii CM.
Essays Biochem. 2018 Jul 20;62(3):467-481. doi: 10.1042/EBC20170114. Print 2018 Jul 20.
Therapeutic benefit of idebenone in patients with Leber hereditary optic neuropathy: The LEROS nonrandomized controlled trial.
Yu-Wai-Man P, Carelli V, Newman NJ, Silva MJ, Linden A, Van Stavern G, Szaflik JP, Banik R, Lubiński W, Pemp B, Liao YJ, Subramanian PS, Misiuk-Hojło M, Newman S, Castillo L, Kocięcki J, Levin MH, Muñoz-Negrete FJ, Yagan A, Cherninkova S, Katz D, Meunier A, Votruba M, Korwin M, Dziedziak J, Jurkutė N, Harvey JP, La Morgia C, Priglinger C, Llòria X, Tomasso L, Klopstock T; LEROS Study Group.
Cell Rep Med. 2024 Mar 19;5(3):101437. doi: 10.1016/j.xcrm.2024.101437. Epub 2024 Feb 29.
Mitochondrial Disorders.
Klopstock T, Priglinger C, Yilmaz A, Kornblum C, Distelmaier F, Prokisch H.
Dtsch Arztebl Int. 2021 Nov 5;118(44):741-748. doi: 10.3238/arztebl.m2021.0251.
Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy.
Newman NJ, Yu-Wai-Man P, Subramanian PS, Moster ML, Wang AG, Donahue SP, Leroy BP, Carelli V, Biousse V, Vignal-Clermont C, Sergott RC, Sadun AA, Rebolleda Fernández G, Chwalisz BK, Banik R, Bazin F, Roux M, Cox ED, Taiel M, Sahel JA; LHON REFLECT Study Group.
Brain. 2023 Apr 19;146(4):1328-1341. doi: 10.1093/brain/awac421.
Leber hereditary optic neuropathy: new and emerging therapies.
Davila-Siliezar P, Carter M, Milea D, Lee AG.
Curr Opin Ophthalmol. 2022 Nov 1;33(6):574-578. doi: 10.1097/ICU.0000000000000891. Epub 2022 Aug 24.
Leber's Hereditary Optic Neuropathy: Novel Views and Persisting Challenges.
Jancic J, Samardzic J, Stojanovic S, Stojanovic A, Milanovic AM, Nikolic B, Ivancevic N, Kostic V.
CNS Neurol Disord Drug Targets. 2017;16(8):927-935. doi: 10.2174/1871527316666170724172455.
Gene Therapy for Leber's Hereditary Optic Neuropathy: Time to Include a True Placebo Arm?
Wang Q, Milea D, Lee AG.
Am J Ophthalmol. 2022 Sep;241:A11-A12. doi: 10.1016/j.ajo.2022.05.018. Epub 2022 May 27.
Neuroimaging in Leber Hereditary Optic Neuropathy: State-of-the-art and future prospects.
Chow-Wing-Bom HT, Callaghan MF, Wang J, Wei S, Dick F, Yu-Wai-Man P, Dekker TM.
Neuroimage Clin. 2022;36:103240. doi: 10.1016/j.nicl.2022.103240. Epub 2022 Oct 25.
Leber hereditary optic neuropathy.
Yu-Wai-Man P, Turnbull DM, Chinnery PF.
J Med Genet. 2002 Mar;39(3):162-9. doi: 10.1136/jmg.39.3.162.
